Name: Zipchip CE Mass Spectrometry 908 Devices System
Brand: Zipchip
SKU: 1557
Availability: InStock

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Zipchip CE Mass Spectrometry 908 Devices System

Original price was: $32,880.00.Current price is: $16,440.00.

ZipChip separations, in contrast to liquid chromatography, are intrinsically nano. This implies that speed and sensitivity are not traded off, and you don’t have to be an expert to get the best results. With just nanoliters of material injected, ZipChip can usually provide excellent analyte separations in 3 minutes. A mass spectrometer can now study big molecules in their entire, near-native states and provide useful molecular information on each species found. ZipChip is a microfluidic device that completely combines electrospray ionization (ESI) with capillary electrophoresis (CE). This removes the “dead volumes” that are typical of conventional capillary-based techniques as well as failure-prone connections between distinct components. Fast separations are the end product, with no failure points, band broadening, or lost time.

Categories: Surveying Equipment, Tester Tag: Zipchip Brand: Zipchip

Description

Zipchip CE Mass Spectrometry 908 Devices

High-Resolution Separation

ZipChip utilizes capillary electrophoresis (CE) integrated with mass spectrometry (MS). This combination allows for high-resolution separation of complex mixtures based on charge-to-mass ratios. It can differentiate and analyze molecules that may be challenging to distinguish using other techniques. This makes it highly effective for the assessment of critical quality attributes (CQAs) such as post-translational modifications in proteins, peptide mapping, and the analysis of small molecules.

Rapid Analysis

Significantly reduce analysis time compared to traditional methods. ZipChip can perform analyses in minutes, whereas a traditional capillary electrophoresis instrument or liquid chromatography (LC) methods might take much longer. This rapid turnaround is crucial for timely decision-making in research and manufacturing processes. The image above shows peptide mapping of the NIST mAb, with analysis done on the ZipChip in under 8 minutes. This could take hours on an LC MS system.

Minimal Sample Preparation

The ZipChip CE-MS device requires minimal sample preparation, which reduces the risk of sample loss or modification during preparation. This feature is particularly important for maintaining the integrity of the sample and ensuring accurate analysis of critical quality attributes (CQAs).

Integration with Mass Spectrometry

By integrating a capillary electrophoresis separation with mass spectrometry, you receive detailed molecular information, including molecular weight and structural data, unlike UV-detection based capillary electrophoresis separations. This integration is invaluable for identifying and quantifying critical quality attributes (CQAs), understanding their impact on product quality, and ensuring regulatory compliance.

Sample Tray Cooling:
Integrated Peltier Cooling: Range: 4ºC to Ambient -3ºC (at relative humidity of 80% and ambient temperature of 25ºC)

Software:
– ZipChip software for configuration and set up of sequences and run parameters.
– Routines for automated chip priming and unattended operation

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